Publications from Center Staff Members

Publications from years 2008, 2007, 2006, 2005, 2004, 2003, 2002, 2001 and 2000

  • 2007

    23. McLaren CE, Gordeuk VR, Chen WP, Barton JC, Acton RT, Speechley M, Castro O, Adams PC, Snively BM, Harris EL, Reboussin DM, McLachlan GJ, Bean R; Hemochromatosis and Iron Overload Screening Study Research Investigators. Bivariate mixture modeling of transferrin saturation and serum ferritinconcentration in Asians, African Americans, Hispanics, and whites in the Hemochromatosis and Iron Overload Screening (HEIRS) Study.Transl Res. 2008 Feb;151(2):97-109. Epub 2007 Nov 9.PMID: 18201677 [PubMed - in process]

    22. Hamid A, Wani NA, Rana S, Vaiphei K, Mahmood A, Kaur J. Down-regulation of reduced folate carrier may result in folate malabsorption across intestinal brush border membrane during experimental alcoholism. FEBS J. 2007 Dec;274(24):6317-28. Epub 2007 Nov 12. PMID: 18005257 [PubMed - indexed for MEDLINE]

    21. Rana S, Kundu B, Durani S. A mixed-alpha,beta miniprotein stereochemically reprogrammed to high-binding affinity for acetylcholine. Biopolymers. 2007 Nov;87(4):231-43. PMID: 17879332 [PubMed - indexed for MEDLINE]

    20. Adams PC, Reboussin DM, Press RD, Barton JC, Acton RT, Moses GC,Leiendecker-Foster C, McLaren GD, Dawkins FW, Gordeuk VR, Lovato L, Eckfeldt JH. Biological variability of transferrin saturation and unsaturated iron-binding capacity. Am J Med. 2007 Nov;120(11):999.e1-7.PMID: 17976429 [PubMed - indexed for MEDLINE]

    19. Barton JC, Acton RT, Leiendecker-Foster C, Lovato L, Adams PC, McLaren GD,Eckfeldt JH, McLaren CE, Reboussin DM, Gordeuk VR, Speechley MR, Reiss JA, Press RD, Dawkins FW; Hemochromatosis and Iron Overload Screening (HEIRS) Study Research Investigators. HFE C282Y homozygotes aged 25-29 years at HEIRS Study initial screening.Genet Test. 2007 Fall;11(3):269-75.PMID: 17949288 [PubMed - indexed for MEDLINE]

    18. Hall MA, Barton JC, Adams PC, McLaren CE, Reiss JA, Castro O, Ruggiero A, Acton RT, Power TE, Bent TC. Genetic screening for iron overload: No evidence of discrimination at 1 year.J Fam Pract. 2007 Oct;56(10):829-34.PMID: 17908514 [PubMed - indexed for MEDLINE]

    17. McLaren CE, Barton JC, Gordeuk VR, Wu L, Adams PC, Reboussin DM, Speechley M,Chang H, Acton RT, Harris EL, Ruggiero AM, Castro O; Hemochromatosis and IronOverload Screening Study Research Investigators. Determinants and characteristics of mean corpuscular volume and hemoglobinconcentration in white HFE C282Y homozygotes in the hemochromatosis and ironoverload screening study.Am J Hematol. 2007 Oct;82(10):898-905.PMID: 17597476 [PubMed - indexed for MEDLINE]

    16. Onyekwere OC, Campbell A, Teshome M, Onyeagoro S, Sylvan C, Akintilo A, Hutchinson S, Ensing G, Gaskin P, Kato G, Rana S, Kwagyan J, Gordeuk V, Williams J, Castro O. Pulmonary Hypertension in Children and Adolescents with Sickle Cell Disease.Pediatr Cardiol. 2007 Aug 7; [Epub ahead of print]PMID: 17680298 [PubMed - in process]

    15. Dawkins FW, Gordeuk VR, Snively BM, Lovato L, Barton JC, Acton RT, McLaren GD,Leiendecker-Foster C, McLaren CE, Adams PC, Speechley M, Harris EL, Jackson S,Thomson EJ. African Americans at risk for increased iron stores or liver disease.Am J Med. 2007 Aug;120(8):734.e1-9. Epub 2007 Mar 21.PMID: 17679134 [PubMed - indexed for MEDLINE]

    14. Mukherjee S, Golder D, Rana S, Jana BB. Responses of succinate dehydrogenase and non-specific alkaline phosphatases and mortality of tilapia to ambient pH stress in a sewage-fed aquaculture pond. Indian J Exp Biol. 2007 Jul; 45(7):630-7. PMID: 17821860 [PubMed - indexed for MEDLINE]

    13. Debebe Z, Ammosova T, Jerebtsova M, Kurantsin-Mills J, Niu X, Charles S,Richardson DR, Ray PE, Gordeuk VR, Nekhai S. Iron chelators ICL670 and 311 inhibit HIV-1 transcription.Virology. 2007 Oct 25;367(2):324-33. Epub 2007 Jul 13.PMID: 17631934 [PubMed - indexed for MEDLINE]

    12. Acton RT, Snively BM, Barton JC, McLaren CE, Adams PC, Rich SS, Eckfeldt JH, Press RD, Sholinsky P, Leiendecker-Foster C, McLaren GD, Speechley MR, Harris EL,Dawkins FW, Gordeuk VR; Hemochromatosis and Iron Overload Screening StudyResearch Investigators. A genome-wide linkage scan for iron phenotype quantitative trait loci: the HEIRS Family Study.Clin Genet. 2007 Jun;71(6):518-29.PMID: 17539901 [PubMed - indexed for MEDLINE]

    11. Kasvosve I, Gomo ZA, Nathoo KJ, Matibe P, Mudenge B, Gordeuk VR. Reference intervals of serum transferrin receptors in pre-school children inZimbabwe.Clin Chim Acta. 2007 Jul;382(1-2):138-41. Epub 2007 Apr 11.PMID: 17493600 [PubMed - indexed for MEDLINE]

    10. Boelaert JR, Vandecasteele SJ, Appelberg R, Gordeuk VR. The effect of the host's iron status on tuberculosis.J Infect Dis. 2007 Jun 15;195(12):1745-53. Epub 2007 May 4. Review.PMID: 17492589 [PubMed - indexed for MEDLINE]

    9. Agarwal N, Gordeuk VR, Prchal JT. Are erythropoietin receptors expressed in tumors? Facts and fiction--more carefulstudies are needed.J Clin Oncol. 2007 May 1;25(13):1813-4; author reply 1815. No abstract available.PMID: 17470878 [PubMed - indexed for MEDLINE]

    8. Kato GJ, Onyekwere OC, Gladwin MT. Pulmonary hypertension in sickle cell disease: relevance to children.Pediatr Hematol Oncol. 2007 Apr-May;24(3):159-70. Review.PMID: 17454785 [PubMed - indexed for MEDLINE]

    7. Harris EL, McLaren CE, Reboussin DM, Gordeuk VR, Barton JC, Acton RT, McLarenGD, Vogt TM, Snively BM, Leiendecker-Foster C, Holup JL, Passmore LV, EckfeldtJH, Lin E, Adams PC. Serum ferritin and transferrin saturation in Asians and Pacific Islanders.Arch Intern Med. 2007 Apr 9;167(7):722-6.PMID: 17420432 [PubMed - indexed for MEDLINE]

    6. Rivers CA, Barton JC, Gordeuk VR, Acton RT, Speechley MR, Snively BM,Leiendecker-Foster C, Press RD, Adams PC, McLaren GD, Dawkins FW, McLaren CE,Reboussin DM. Association of ferroportin Q248H polymorphism with elevated levels of serumferritin in African Americans in the Hemochromatosis and Iron Overload Screening (HEIRS) Study.Blood Cells Mol Dis. 2007 May-Jun;38(3):247-52. Epub 2007 Feb 5.PMID: 17276706 [PubMed - indexed for MEDLINE]

    5. Nekhai S, Jerebtsova M, Jackson A, Southerland W. Regulation of HIV-1 transcription by protein phosphatase 1.Curr HIV Res. 2007 Jan;5(1):3-9. Review.PMID: 17266553 [PubMed - indexed for MEDLINE]

    4. Sachdev V, Machado RF, Shizukuda Y, Rao YN, Sidenko S, Ernst I, St Peter M,Coles WA, Rosing DR, Blackwelder WC, Castro O, Kato GJ, Gladwin MT. Diastolic dysfunction is an independent risk factor for death in patients withsickle cell disease.J Am Coll Cardiol. 2007 Jan 30;49(4):472-9. Epub 2007 Jan 16.PMID: 17258093 [PubMed - indexed for MEDLINE]

    3. Berro R, de la Fuente C, Klase Z, Kehn K, Parvin L, Pumfery A, Agbottah E,Vertes A, Nekhai S, Kashanchi F. Identifying the membrane proteome of HIV-1 latently infected cells.J Biol Chem. 2007 Mar 16;282(11):8207-18. Epub 2007 Jan 19.PMID: 17237230 [PubMed - indexed for MEDLINE]

    2. Vichinsky E, Onyekwere O, Porter J, Swerdlow P, Eckman J, Lane P, Files B,Hassell K, Kelly P, Wilson F, Bernaudin F, Forni GL, Okpala I, Ressayre-DjafferC, Alberti D, Holland J, Marks P, Fung E, Fischer R, Mueller BU, Coates T;Deferasirox in Sickle Cell Investigators. A randomised comparison of deferasirox versus deferoxamine for the treatment oftransfusional iron overload in sickle cell disease.Br J Haematol. 2007 Feb;136(3):501-8.PMID: 17233848 [PubMed - indexed for MEDLINE]

    1. Nekhai S, Bhat UG, Ammosova T, Radhakrishnan SK, Jerebtsova M, Niu X, Foster A, Layden TJ, Gartel AL. A novel anticancer agent ARC antagonizes HIV-1 and HCV.Oncogene. 2007 May 31;26(26):3899-903. Epub 2006 Dec 18.PMID: 17173067 [PubMed - indexed for MEDLINE]

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  • 2006

    • 19. Nekhai S, Jeang KT. Transcriptional and post-transcriptional regulation of HIV-1 gene expression:role of cellular factors for Tat and Rev.Future Microbiol. 2006 Dec;1:417-26. Review.PMID: 17661632 [PubMed - indexed for MEDLINE]

    18. Ammosova T, Berro R, Jerebtsova M, Jackson A, Charles S, Klase Z, Southerland W, Gordeuk VR, Kashanchi F, Nekhai S. Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription.Retrovirology. 2006 Nov 3;3:78.PMID: 17083724 [PubMed - indexed for MEDLINE]

    17. Epie N, Ammosova T, Turner W, Nekhai S. Inhibition of PP2A by LIS1 increases HIV-1 gene expression.Retrovirology. 2006 Oct 2;3:65.PMID: 17018134 [PubMed - indexed for MEDLINE]

    16. McLaren CE, Li KT, McLaren GD, Gordeuk VR, Snively BM, Reboussin DM, BartonJC, Acton RT, Dawkins FW, Harris EL, Eckfeldt JH, Moses GC, Adams PC. Mixture models of serum iron measures in population screening for hemochromatosisand iron overload.Transl Res. 2006 Oct;148(4):196-206.PMID: 17002922 [PubMed - indexed for MEDLINE]

    15. Laurence B, Woods D, George D, Onyekwere O, Katz R, Lanzkron S, Diener-WestM, Powe N. Self-perceived loss of control and untreated dental decay in African Americanadults with and without sickle cell disease.J Health Care Poor Underserved. 2006 Aug;17(3):641-51.PMID: 16960327 [PubMed - indexed for MEDLINE]

    14. Acton RT, Barton JC, Passmore LV, Adams PC, Speechley MR, Dawkins FW,Sholinsky P, Reboussin DM, McLaren GD, Harris EL, Bent TC, Vogt TM, Castro O. Relationships of serum ferritin, transferrin saturation, and HFE mutations andself-reported diabetes in the Hemochromatosis and Iron Overload Screening (HEIRS)study.Diabetes Care. 2006 Sep;29(9):2084-9.PMID: 16936157 [PubMed - indexed for MEDLINE]

    13. Darbari DS, Kple-Faget P, Kwagyan J, Rana S, Gordeuk VR, Castro O. Circumstances of death in adult sickle cell disease patients.Am J Hematol. 2006 Nov;81(11):858-63.PMID: 16924640 [PubMed - indexed for MEDLINE]

    12. Little JA, McGowan VR, Kato GJ, Partovi KS, Feld JJ, Maric I, Martyr S,Taylor JG 6th, Machado RF, Heller T, Castro O, Gladwin MT. Combination erythropoietin-hydroxyurea therapy in sickle cell disease: experiencefrom the National Institutes of Health and a literature review.Haematologica. 2006 Aug;91(8):1076-83.PMID: 16885048 [PubMed - indexed for MEDLINE]

    11. Machado RF, Anthi A, Steinberg MH, Bonds D, Sachdev V, Kato GJ,Taveira-DaSilva AM, Ballas SK, Blackwelder W, Xu X, Hunter L, Barton B, Waclawiw M, Castro O, Gladwin MT; MSH Investigators. N-terminal pro-brain natriuretic peptide levels and risk of death in sickle cell disease.JAMA. 2006 Jul 19;296(3):310-8.PMID: 16849664 [PubMed - indexed for MEDLINE]

    10. Adams PC, Passmore L, Chakrabarti S, Reboussin DM, Acton RT, Barton JC,McLaren GD, Eckfeldt JH, Dawkins FW, Gordeuk VR, Harris EL, Leiendecker-Foster C,Gossman E, Sholinsky P; Hemochromatosis and Iron Overload Screening StudyResearch Investigators. Liver diseases in the hemochromatosis and iron overload screening study.Clin Gastroenterol Hepatol. 2006 Jul;4(7):918-23; quiz 807.PMID: 16797244 [PubMed - indexed for MEDLINE]

    9. Pumfery A, de la Fuente C, Berro R, Nekhai S, Kashanchi F, Chao SH. Potential use of pharmacological cyclin-dependent kinase inhibitors as anti-HIVtherapeutics.Curr Pharm Des. 2006;12(16):1949-61. Review.PMID: 16787240 [PubMed - indexed for MEDLINE]

    8. Bushuev VI, Miasnikova GY, Sergueeva AI, Polyakova LA, Okhotin D, Gaskin PR, Debebe Z, Nekhai S, Castro OL, Prchal JT, Gordeuk VR. Endothelin-1, vascular endothelial growth factor and systolic pulmonary arterypressure in patients with Chuvash polycythemia.Haematologica. 2006 Jun;91(6):744-9.PMID: 16769575 [PubMed - indexed for MEDLINE]

    7. Gordeuk VR, Onojobi G, Schneider MF, Dawkins FW, Delapenha R, Voloshin Y, vonWyl V, Bacon M, Minkoff H, Levine A, Cohen M, Greenblatt RM. The association of serum ferritin and transferrin receptor concentrations withmortality in women with human immunodeficiency virus infection.Haematologica. 2006 Jun;91(6):739-43. Epub 2006 May 16.PMID: 16704960 [PubMed - indexed for MEDLINE]

    6. Gordeuk VR, Prchal JT. Vascular complications in Chuvash polycythemia.Semin Thromb Hemost. 2006 Apr;32(3):289-94. Review.PMID: 16673284 [PubMed - indexed for MEDLINE]

    5. McDevitt MA, Xie J, Shanmugasundaram G, Griffith J, Liu A, McDonald C, Thuma P, Gordeuk VR, Metz CN, Mitchell R, Keefer J, David J, Leng L, Bucala R. A critical role for the host mediator macrophage migration inhibitory factor inthe pathogenesis of malarial anemia.J Exp Med. 2006 May 15;203(5):1185-96. Epub 2006 Apr 24.PMID: 16636133 [PubMed - indexed for MEDLINE]

    4. Kasvosve I, Gomo ZA, Nathoo KJ, Matibe P, Mudenge B, Loyevsky M, Nekhai S,Gordeuk VR. Association of serum transferrin receptor concentration with markers ofinflammation in Zimbabwean children.Clin Chim Acta. 2006 Sep;371(1-2):130-6. Epub 2006 Apr 17.PMID: 16603144 [PubMed - indexed for MEDLINE]

    3. Kamineni P, Chirla S, Dinh K, Hasan S, Nidhiry E, Kwagyan J, Naab T, LombardoF, Castro O, Dawkins F. Low cobalamin levels in African Americans with and without sickle cell disease.J Natl Med Assoc. 2006 Mar;98(3):352-6.PMID: 16573298 [PubMed - indexed for MEDLINE]

    2. Nekhai S, Jerebtsova M. Therapies for HIV with RNAi.Curr Opin Mol Ther. 2006 Feb;8(1):52-61. Review.PMID: 16506526 [PubMed - indexed for MEDLINE]

    1. Barton JC, Acton RT, Lovato L, Speechley MR, McLaren CE, Harris EL, ReboussinDM, Adams PC, Dawkins FW, Gordeuk VR, Walker AP; Hemochromatosis and IronOverload Screening Study Research Investigators. Initial screening transferrin saturation values, serum ferritin concentrations,and HFE genotypes in Native Americans and whites in the Hemochromatosis and Iron Overload Screening Study.Clin Genet. 2006 Jan;69(1):48-57.PMID: 16451136 [PubMed - indexed for MEDLINE]

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  • 2005

    • 21. McNamara L, Gordeuk VR, MacPhail AP. Ferroportin (Q248H) mutations in African families with dietary iron overload.J Gastroenterol Hepatol. 2005 Dec;20(12):1855-8.PMID: 16336444 [PubMed - indexed for MEDLINE]

    20. Weiss G, Gordeuk VR. Benefits and risks of iron therapy for chronic anaemias.Eur J Clin Invest. 2005 Dec;35 Suppl 3:36-45. Review.PMID: 16281957 [PubMed - indexed for MEDLINE]

    19. Kasvosve I, Gomo ZA, Nathoo KJ, Matibe P, Mudenge B, Loyevsky M, Gordeuk VR. Effect of ferroportin Q248H polymorphism on iron status in African children.Am J Clin Nutr. 2005 Nov;82(5):1102-6.PMID: 16280445 [PubMed - indexed for MEDLINE]

    18. Barton JC, Acton RT, Dawkins FW, Adams PC, Lovato L, Leiendecker-Foster C,McLaren CE, Reboussin DM, Speechley MR, Gordeuk VR, McLaren GD, Sholinsky P,Harris EL. Initial screening transferrin saturation values, serum ferritin concentrations,and HFE genotypes in whites and blacks in the Hemochromatosis and Iron OverloadScreening Study.Genet Test. 2005 Fall;9(3):231-41.PMID: 16225403 [PubMed - indexed for MEDLINE]

    17. Gordeuk VR. Genetics, diagnosis and treatment of hemochromatosis.Clin Adv Hematol Oncol. 2003 Apr;1(4):216-7. No abstract available.PMID: 16224408 [PubMed - indexed for MEDLINE]

    16. Castro O, Gladwin MT. Pulmonary hypertension in sickle cell disease: mechanisms, diagnosis, andmanagement.Hematol Oncol Clin North Am. 2005 Oct;19(5):881-96, vii. Review.PMID: 16214649 [PubMed - indexed for MEDLINE]

    15. Castro O, Gladwin MT, Kopterides P, Fremont R, Medoff BD. Case 17-2005: acute chest syndrome and ARDS.N Engl J Med. 2005 Oct 6;353(14):1529-30; author reply 1529-30. No abstractavailable.PMID: 16207862 [PubMed - indexed for MEDLINE]

    14. Castro O, Lombardo FA, Gordeuk VR. The celestial fire of conscience.N Engl J Med. 2005 Sep 22;353(12):1301-2; author reply 1301-2. No abstractavailable.PMID: 16180278 [PubMed - indexed for MEDLINE]

    13. Sierralta WD, Kohen P, Castro O, Mu ñoz A, Strauss JF 3rd, Devoto L. Ultrastructural and biochemical evidence for the presence of mature steroidogenicacute regulatory protein (StAR) in the cytoplasm of human luteal cells.Mol Cell Endocrinol. 2005 Oct 20;242(1-2):103-10.PMID: 16162390 [PubMed - indexed for MEDLINE]

    12. Tavakkoli F, Nahavandi M, Wyche MQ, Castro O. Effects of hydroxyurea treatment on cerebral oxygenation in adult patients withsickle cell disease: an open-label pilot study.Clin Ther. 2005 Jul;27(7):1083-8.PMID: 16154487 [PubMed - indexed for MEDLINE]

    11. Ammosova T, Jerebtsova M, Beullens M, Lesage B, Jackson A, Kashanchi F,Southerland W, Gordeuk VR, Bollen M, Nekhai S. Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein.J Biol Chem. 2005 Oct 28;280(43):36364-71. Epub 2005 Aug 29.PMID: 16131488 [PubMed - indexed for MEDLINE]

    10. Ammosova T, Berro R, Kashanchi F, Nekhai S. RNA interference directed to CDK2 inhibits HIV-1 transcription.Virology. 2005 Oct 25;341(2):171-8. Epub 2005 Aug 8.PMID: 16085226 [PubMed - indexed for MEDLINE]

    9. Ammosova T, Washington K, Debebe Z, Brady J, Nekhai S. Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.Retrovirology. 2005 Jul 27;2:47.PMID: 16048649 [PubMed - indexed for MEDLINE]

    8. Machado RF, Martyr S, Kato GJ, Barst RJ, Anthi A, Robinson MR, Hunter L,Coles W, Nichols J, Hunter C, Sachdev V, Castro O, Gladwin MT. Sildenafil therapy in patients with sickle cell disease and pulmonaryhypertension.Br J Haematol. 2005 Aug;130(3):445-53.PMID: 16042696 [PubMed - indexed for MEDLINE]

    7. Hodges M, Yikilmaz E, Patterson G, Kasvosve I, Rouault TA, Gordeuk VR,Loyevsky M. An iron regulatory-like protein expressed in Plasmodium falciparum displaysaconitase activity.Mol Biochem Parasitol. 2005 Sep;143(1):29-38.PMID: 15963579 [PubMed - indexed for MEDLINE]

    6. Adams PC, Reboussin DM, Barton JC, McLaren CE, Eckfeldt JH, McLaren GD,Dawkins FW, Acton RT, Harris EL, Gordeuk VR, Leiendecker-Foster C, Speechley M,Snively BM, Holup JL, Thomson E, Sholinsky P; Hemochromatosis and Iron OverloadScreening (HEIRS) Study Research Investigators. Hemochromatosis and iron-overload screening in a racially diverse population.N Engl J Med. 2005 Apr 28;352(17):1769-78.PMID: 15858186 [PubMed - indexed for MEDLINE]

    5. Gordeuk VR. Efficacy and safety of sildenafil in the treatment of severe pulmonaryhypertension in patients with hemoglobinopathies.Haematologica. 2005 Apr;90(4):433-4. No abstract available.PMID: 15820926 [PubMed - indexed for MEDLINE]

    4. Kwagyan J, Tabe CE, Xu S, Maqbool AR, Gordeuk VR, Randall OS. The impact of body mass index on pulse pressure in obesity.J Hypertens. 2005 Mar;23(3):619-24.PMID: 15716705 [PubMed - indexed for MEDLINE]

    3. Epie N, Ammosova T, Sapir T, Voloshin Y, Lane WS, Turner W, Reiner O, Nekhai S. HIV-1 Tat interacts with LIS1 protein.Retrovirology. 2005 Feb 7;2:6.PMID: 15698475 [PubMed - indexed for MEDLINE]

    2. Gordeuk VR, Stockton DW, Prchal JT. Congenital polycythemias/erythrocytoses.Haematologica. 2005 Jan;90(1):109-16. Review.PMID: 15642677 [PubMed - indexed for MEDLINE]

    1. Kassim OO, Loyevsky M, Elliott B, Geall A, Amonoo H, Gordeuk VR. Effects of root extracts of Fagara zanthoxyloides on the in vitro growth andstage distribution of Plasmodium falciparum.Antimicrob Agents Chemother. 2005 Jan;49(1):264-8.PMID: 15616304 [PubMed - indexed for MEDLINE]

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  • 2004

    • 9. Geall AJ, Baugh JA, Loyevsky M, Gordeuk VR, Al-Abed Y, Bucala R. Targeting malaria with polyamines.Bioconjug Chem. 2004 Nov-Dec;15(6):1161-5.PMID: 15546180 [PubMed - indexed for MEDLINE]

    8. Agbottah E, de La Fuente C, Nekhai S, Barnett A, Gianella-Borradori A,Pumfery A, Kashanchi F. Antiviral activity of CYC202 in HIV-1-infected cells.J Biol Chem. 2005 Jan 28;280(4):3029-42. Epub 2004 Nov 5.PMID: 15531588 [PubMed - indexed for MEDLINE]

    7. Randall OS, Retta TM, Kwagyan J, Gordeuk VR, Xu S, Maqbool AR, Ketete M,Obisesan TO. Obese African Americans: the prevalence of dyslipidemia, hypertension, anddiabetes mellitus.Ethn Dis. 2004 Summer;14(3):384-8.PMID: 15328940 [PubMed - indexed for MEDLINE]

    6. Gladwin MT, Sachdev V, Jison ML, Shizukuda Y, Plehn JF, Minter K, Brown B,Coles WA, Nichols JS, Ernst I, Hunter LA, Blackwelder WC, Schechter AN, RodgersGP, Castro O, Ognibene FP. Pulmonary hypertension as a risk factor for death in patients with sickle celldisease.N Engl J Med. 2004 Feb 26;350(9):886-95.PMID: 14985486 [PubMed - indexed for MEDLINE]

    5. Hasan S, Elbedawi M, Castro O, Gladwin M, Palestine A. Central retinal vein occlusion in sickle cell disease.South Med J. 2004 Feb;97(2):202-4.PMID: 14982276 [PubMed - indexed for MEDLINE]

    4. McDevitt MA, Xie J, Gordeuk V, Bucala R. The anemia of malaria infection: role of inflammatory cytokines.Curr Hematol Rep. 2004 Mar;3(2):97-106. Review.PMID: 14965485 [PubMed - indexed for MEDLINE]

    3. Nahavandi M, Tavakkoli F, Hasan SP, Wyche MQ, Castro O. Cerebral oximetry in patients with sickle cell disease.Eur J Clin Invest. 2004 Feb;34(2):143-8.PMID: 14764078 [PubMed - indexed for MEDLINE]

    2. Gordeuk VR, Sergueeva AI, Miasnikova GY, Okhotin D, Voloshin Y, Choyke PL,Butman JA, Jedlickova K, Prchal JT, Polyakova LA. Congenital disorder of oxygen sensing: association of the homozygous Chuvashpolycythemia VHL mutation with thrombosis and vascular abnormalities but nottumors.Blood. 2004 May 15;103(10):3924-32. Epub 2004 Jan 15.PMID: 14726398 [PubMed - indexed for MEDLINE]

    1. Walcourt A, Loyevsky M, Lovejoy DB, Gordeuk VR, Richardson DR. Novel aroylhydrazone and thiosemicarbazone iron chelators with anti-malarialactivity against chloroquine-resistant and -sensitive parasites.Int J Biochem Cell Biol. 2004 Mar;36(3):401-7.PMID: 14687919 [PubMed - indexed for MEDLINE]

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  • 2003

    • 15. Gordeuk VR, Caleffi A, Corradini E, Ferrara F, Jones RA, Castro O, Onyekwere O, Kittles R, Pignatti E, Montosi G, Garuti C, Gangaidzo IT, Gomo ZA, Moyo VM,Rouault TA, MacPhail P, Pietrangelo A. Iron overload in Africans and African-Americans and a common mutation in theSCL40A1 (ferroportin 1) gene.Blood Cells Mol Dis. 2003 Nov-Dec;31(3):299-304.PMID: 14636642 [PubMed - indexed for MEDLINE]

    14. Hassan M, Hasan S, Giday S, Alamgir L, Banks A, Frederick W, Smoot D, Castro O. Hepatitis C virus in sickle cell disease.J Natl Med Assoc. 2003 Oct;95(10):939-42.PMID: 14620705 [PubMed - indexed for MEDLINE]

    13. Liu E, Percy MJ, Amos CI, Guan Y, Shete S, Stockton DW, McMullin MF,Polyakova LA, Ang SO, Pastore YD, Jedlickova K, Lappin TR, Gordeuk V, Prchal JT. The worldwide distribution of the VHL 598C>T mutation indicates a single foundingevent.Blood. 2004 Mar 1;103(5):1937-40. Epub 2003 Nov 6.PMID: 14604959 [PubMed - indexed for MEDLINE]

    12. Boelaert JR, Gomes MS, Gordeuk VR. Smoking, iron, and tuberculosis.Lancet. 2003 Oct 11;362(9391):1243-4. No abstract available.PMID: 14568761 [PubMed - indexed for MEDLINE]

    11. Hassan M, Hasan S, Castro O, Giday S, Banks A, Smoot D. HCV in sickle cell disease.J Natl Med Assoc. 2003 Sep;95(9):864-7, 872-4. Review.PMID: 14527056 [PubMed - indexed for MEDLINE]

    10. McNamara L, Panz VR, Raal FJ, Paiker J, Joffe BI, Gordeuk VR, MacPhail AP. Basal endocrine status in African dietary iron overload.Endocrine. 2003 Aug;21(3):241-4.PMID: 14515008 [PubMed - indexed for MEDLINE]

    9. Hasan SP, Hashmi S, Alhassen M, Lawson W, Castro O. Depression in sickle cell disease.J Natl Med Assoc. 2003 Jul;95(7):533-7.PMID: 12911250 [PubMed - indexed for MEDLINE]

    8. McLaren CE, Li KT, Garner CP, Beutler E, Gordeuk VR. Mixture distribution analysis of phenotypic markers reflecting HFE genemutations.Blood. 2003 Dec 15;102(13):4563-6. Epub 2003 Aug 7.PMID: 12907432 [PubMed - indexed for MEDLINE]

    7. Ammosova T, Jerebtsova M, Beullens M, Voloshin Y, Ray PE, Kumar A, Bollen M, Nekhai S. Nuclear protein phosphatase-1 regulates HIV-1 transcription.J Biol Chem. 2003 Aug 22;278(34):32189-94. Epub 2003 Jun 4.PMID: 12788939 [PubMed - indexed for MEDLINE]

    6. Steinberg MH, Barton F, Castro O, Pegelow CH, Ballas SK, Kutlar A, OrringerE, Bellevue R, Olivieri N, Eckman J, Varma M, Ramirez G, Adler B, Smith W, CarlosT, Ataga K, DeCastro L, Bigelow C, Saunthararajah Y, Telfer M, Vichinsky E,Claster S, Shurin S, Bridges K, Waclawiw M, Bonds D, Terrin M. Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia:risks and benefits up to 9 years of treatment.JAMA. 2003 Apr 2;289(13):1645-51. Erratum in: JAMA. 2003 Aug 13;290(6):756.PMID: 12672732 [PubMed - indexed for MEDLINE]

    5. Prasad R, Hasan S, Castro O, Perlin E, Kim K. Long-term outcomes in patients with sickle cell disease and frequentvaso-occlusive crises.Am J Med Sci. 2003 Mar;325(3):107-9.PMID: 12640284 [PubMed - indexed for MEDLINE]

    4. Darbari D, Loyevsky M, Gordeuk V, Kark JA, Castro O, Rana S, Apprey V,Kurantsin-Mills J. Fluorescence measurements of the labile iron pool of sickle erythrocytes.Blood. 2003 Jul 1;102(1):357-64. Epub 2003 Mar 6.PMID: 12623854 [PubMed - indexed for MEDLINE]

    3. Loyevsky M, Mompoint F, Yikilmaz E, Altschul SF, Madden T, Wootton JC,Kurantsin-Mills J, Kassim OO, Gordeuk VR, Rouault TA. Expression of a recombinant IRP-like Plasmodium falciparum protein thatspecifically binds putative plasmodial IREs.Mol Biochem Parasitol. 2003 Feb;126(2):231-8.PMID: 12615322 [PubMed - indexed for MEDLINE]

    2. Houston-Yu P, Rana SR, Beyer B, Castro O. Frequent and prolonged hospitalizations: a risk factor for early mortality insickle cell disease patients.Am J Hematol. 2003 Mar;72(3):201-3.PMID: 12605392 [PubMed - indexed for MEDLINE]

    1. McLaren CE, Barton JC, Adams PC, Harris EL, Acton RT, Press N, Reboussin DM, McLaren GD, Sholinsky P, Walker AP, Gordeuk VR, Leiendecker-Foster C, Dawkins FW,Eckfeldt JH, Mellen BG, Speechley M, Thomson E; Hemochromatosis and Iron OverloadStudy Research Investigators. Hemochromatosis and Iron Overload Screening (HEIRS) study design for anevaluation of 100,000 primary care-based adults.Am J Med Sci. 2003 Feb;325(2):53-62.PMID: 12589228 [PubMed - indexed for MEDLINE]

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  • 2002

    • 16. Gordeuk VR, Loyevsky M. Antimalarial effect of iron chelators.Adv Exp Med Biol. 2002;509:251-72. Review. No abstract available.PMID: 12572998 [PubMed - indexed for MEDLINE]

    15. Steinberg MH, Voskaridou E, Kutlar A, Loukopoulos D, Koshy M, Ballas SK,Castro O, Barton F. Concordant fetal hemoglobin response to hydroxyurea in siblings with sickle cell disease.Am J Hematol. 2003 Feb;72(2):121-6.PMID: 12555216 [PubMed - indexed for MEDLINE]

    14. Nahavandi M, Tavakkoli F, Wyche MQ, Perlin E, Winter WP, Castro O. Nitric oxide and cyclic GMP levels in sickle cell patients receiving hydroxyurea.Br J Haematol. 2002 Dec;119(3):855-7.PMID: 12437671 [PubMed - indexed for MEDLINE]

    13. Ang SO, Chen H, Hirota K, Gordeuk VR, Jelinek J, Guan Y, Liu E, Sergueeva AI,Miasnikova GY, Mole D, Maxwell PH, Stockton DW, Semenza GL, Prchal JT. Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia.Nat Genet. 2002 Dec;32(4):614-21. Epub 2002 Nov 4.PMID: 12415268 [PubMed - indexed for MEDLINE]

    12. Castro O, Hoque M, Brown BD. Pulmonary hypertension in sickle cell disease: cardiac catheterization resultsand survival.Blood. 2003 Feb 15;101(4):1257-61. Epub 2002 Oct 3.PMID: 12393669 [PubMed - indexed for MEDLINE]

    11. Kasvosve I, Gordeuk VR, Delanghe JR, Gomo ZA, Gangaidzo IT, Khumalo H, MoyoVM, Saungweme T, Mvundura E, Boelaert JR. Iron status in black persons is not influenced by haptoglobin polymorphism.Clin Chem Lab Med. 2002 Aug;40(8):810-3.PMID: 12392310 [PubMed - indexed for MEDLINE]

    10. Boelaert JR, Gordeuk VR. Protein energy malnutrition and risk of tuberculosis infection.Lancet. 2002 Oct 5;360(9339):1102. No abstract available.PMID: 12384022 [PubMed - indexed for MEDLINE]

    9. Gordeuk VR. African iron overload.Semin Hematol. 2002 Oct;39(4):263-9. Review.PMID: 12382201 [PubMed - indexed for MEDLINE]74: Ferguson RP, Arun A, Carter C, Walker SD, Castro O. Hydroxyurea treatment of sickle cell anemia in hospital-based practices.Am J Hematol. 2002 Aug;70(4):326-8.PMID: 12214583 [PubMed - indexed for MEDLINE]

    8. Washington K, Ammosova T, Beullens M, Jerebtsova M, Kumar A, Bollen M, NekhaiS. Protein phosphatase-1 dephosphorylates the C-terminal domain of RNApolymerase-II.J Biol Chem. 2002 Oct 25;277(43):40442-8. Epub 2002 Aug 15.PMID: 12185079 [PubMed - indexed for MEDLINE]

    7. Bianco C, Brittenham G, Gilcher RO, Gordeuk VR, Kushner JP, Sayers M,Chambers L, Counts RB, Aylesworth C, Nemo G, Alving B. Maintaining iron balance in women blood donors of childbearing age: summary of a workshop.Transfusion. 2002 Jun;42(6):798-805. No abstract available.PMID: 12147035 [PubMed - indexed for MEDLINE]

    6. Castro O, Sandler SG, Houston-Yu P, Rana S. Predicting the effect of transfusing only phenotype-matched RBCs to patients withsickle cell disease: theoretical and practical implications.Transfusion. 2002 Jun;42(6):684-90.PMID: 12147019 [PubMed - indexed for MEDLINE]

    5. Deng L, Ammosova T, Pumfery A, Kashanchi F, Nekhai S. HIV-1 Tat interaction with RNA polymerase II C-terminal domain (CTD) and adynamic association with CDK2 induce CTD phosphorylation and transcription fromHIV-1 promoter.J Biol Chem. 2002 Sep 13;277(37):33922-9. Epub 2002 Jul 11.PMID: 12114499 [PubMed - indexed for MEDLINE]

    4. Nahavandi M, Millis RM, Tavakkoli F, Wyche MQ, Perlin E, Winter WP, CastroO. Arterialization of peripheral venous blood in sickle cell disease.J Natl Med Assoc. 2002 May;94(5):320-6.PMID: 12069211 [PubMed - indexed for MEDLINE]

    3. Nekhai S, Zhou M, Fernandez A, Lane WS, Lamb NJ, Brady J, Kumar A. HIV-1 Tat-associated RNA polymerase C-terminal domain kinase, CDK2,phosphorylates CDK7 and stimulates Tat-mediated transcription.Biochem J. 2002 Jun 15;364(Pt 3):649-57.PMID: 12049628 [PubMed - indexed for MEDLINE]

    2. Bharucha DC, Zhou M, Nekhai S, Brady JN, Shukla RR, Kumar A. A protein phosphatase from human T cells augments tat transactivation of thehuman immunodeficiency virus type 1 long-terminal repeat.Virology. 2002 Apr 25;296(1):6-16.PMID: 12036313 [PubMed - indexed for MEDLINE]

    1. Ang SO, Chen H, Gordeuk VR, Sergueeva AI, Polyakova LA, Miasnikova GY,Kralovics R, Stockton DW, Prchal JT. Endemic polycythemia in Russia: mutation in the VHL gene.Blood Cells Mol Dis. 2002 Jan-Feb;28(1):57-62.PMID: 11987242 [PubMed - indexed for MEDLINE]

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  • 2001

    • 9. Goudeau C, Loyevsky M, Kassim OO, Gordeuk VR, Nick H. Assessment of antimalarial effect of ICL670A on in vitro cultures of Plasmodiumfalciparum.Br J Haematol. 2001 Dec;115(4):918-23.PMID: 11843826 [PubMed - indexed for MEDLINE]

    8. Kasvosve I, Delanghe JR, Gomo ZA, Gangaidzo IT, Khumalo H, Langlois MR, MoyoVM, Saungweme T, Mvundura E, Boelaert JR, Gordeuk VR. Effect of transferrin polymorphism on the metabolism of vitamin C in Zimbabweanadults.Am J Clin Nutr. 2002 Feb;75(2):321-5.PMID: 11815325 [PubMed - indexed for MEDLINE]

    7. Wuyts B, Delanghe JR, Kasvosve I, Gordeuk VR, Gangaidzo IT, Gomo ZA. Carbohydrate-deficient transferrin and chronic alcohol ingestion in subjects withtransferrin CD-variants.Clin Chem Lab Med. 2001 Oct;39(10):937-43.PMID: 11758606 [PubMed - indexed for MEDLINE]

    6. Greenberg PL, Gordeuk V, Issaragrisil S, Siritanaratkul N, Fucharoen S,Ribeiro RC. Major hematologic diseases in the developing world- new aspects of diagnosis and management of thalassemia, malarial anemia, and acute leukemia.Hematology Am Soc Hematol Educ Program. 2001;:479-98. Review.PMID: 11723000 [PubMed - indexed for MEDLINE]

    5. Porto G, Cardoso CS, Gordeuk V, Cruz E, Fraga J, Areias J, Oliveira JC,Bravo F, Gangaidzo IT, MacPhail AP, Gomo ZA, Moyo VM, Melo G, Silva C, Justi ça B,de Sousa M. Clinical and genetic heterogeneity in hereditary haemochromatosis: associationbetween lymphocyte counts and expression of iron overload.Eur J Haematol. 2001 Aug;67(2):110-8.PMID: 11722599 [PubMed - indexed for MEDLINE]

    4. Loyevsky M, LaVaute T, Allerson CR, Stearman R, Kassim OO, Cooperman S,Gordeuk VR, Rouault TA. An IRP-like protein from Plasmodium falciparum binds to a mammalianiron-responsive element.Blood. 2001 Oct 15;98(8):2555-62.PMID: 11588054 [PubMed - indexed for MEDLINE]

    3. McLaren CE, Li KT, Gordeuk VR, Hasselblad V, McLaren GD. Relationship between transferrin saturation and iron stores in the AfricanAmerican and US Caucasian populations: analysis of data from the third NationalHealth and Nutrition Examination Survey.Blood. 2001 Oct 15;98(8):2345-51.PMID: 11588029 [PubMed - indexed for MEDLINE]

    2. Zhou M, Nekhai S, Bharucha DC, Kumar A, Ge H, Price DH, Egly JM, Brady JN. TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1transcription.J Biol Chem. 2001 Nov 30;276(48):44633-40. Epub 2001 Sep 25.PMID: 11572868 [PubMed - indexed for MEDLINE]

    1. Gangaidzo IT, Moyo VM, Mvundura E, Aggrey G, Murphree NL, Khumalo H,Saungweme T, Kasvosve I, Gomo ZA, Rouault T, Boelaert JR, Gordeuk VR. Association of pulmonary tuberculosis with increased dietary iron.J Infect Dis. 2001 Oct 1;184(7):936-9. Epub 2001 Aug 17.PMID: 11528590 [PubMed - indexed for MEDLINE]

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  • 2000

    • 17. Nahavandi M, Wyche MQ, Perlin E, Tavakkoli F, Castro O. Nitric Oxide Metabolites in Sickle Cell Anemia Patients after Oral Administrationof Hydroxyurea; Hemoglobinopathy.Hematology. 2000;5(4):335-339.PMID: 11399633 [PubMed - indexed for MEDLINE]

    16. Thuma PE, Bhat GJ, Mabeza GF, Osborne C, Biemba G, Shakankale GM, PeetersPA, Oosterhuis B, Lugt CB, Gordeuk VR. A randomized controlled trial of artemotil (beta-arteether) in Zambian childrenwith cerebral malaria.Am J Trop Med Hyg. 2000 Apr;62(4):524-9.PMID: 11220772 [PubMed - indexed for MEDLINE]

    15. Lounis N, Truffot-Pernot C, Grosset J, Gordeuk VR, Boelaert JR. Iron and Mycobacterium tuberculosis infection.J Clin Virol. 2001 Feb;20(3):123-6. Review.PMID: 11166659 [PubMed - indexed for MEDLINE]

    14. Gordeuk VR, Delanghe JR, Langlois MR, Boelaert JR. Iron status and the outcome of HIV infection: an overview.J Clin Virol. 2001 Feb;20(3):111-5. Review.PMID: 11166657 [PubMed - indexed for MEDLINE]

    13. Castro O, Gordeuk VR, Dawkins F. Caring for the dying--congressional mischief.N Engl J Med. 2000 Apr 6;342(14):1049; author reply 1050. No abstract available.PMID: 10755892 [PubMed - indexed for MEDLINE]

    12. Nekhai S, Bottaro DP, Woldehawariat G, Spellerberg A, Petryshyn R. A cell-permeable peptide inhibits activation of PKR and enhances cellproliferation.Peptides. 2000 Oct;21(10):1449-56.PMID: 11068090 [PubMed - indexed for MEDLINE]

    11. Young RC Jr, Rachal RE, Del Pilar Aguinaga M, Nelson BL, Kim BC, Winter WP, Castro O. Automated oxyhemoglobin dissociation curve construction to assess sickle cellanemia therapy.J Natl Med Assoc. 2000 Sep;92(9):430-5.PMID: 11052456 [PubMed - indexed for MEDLINE]

    10. Kasvosve I, Delanghe JR, Gomo ZA, Gangaidzo IT, Khumalo H, Wuyts B, MvunduraE, Saungweme T, Moyo VM, Boelaert JR, Gordeuk VR. Transferrin polymorphism influences iron status in blacks.Clin Chem. 2000 Oct;46(10):1535-9.PMID: 11017929 [PubMed - indexed for MEDLINE]

    9. Kasvosve I, Gomo ZA, Mvundura E, Moyo VM, Saungweme T, Khumalo H, GordeukVR, Boelaert JR, Delanghe JR, De Bacquer D, Gangaidzo IT. Haptoglobin polymorphism and mortality in patients with tuberculosis.Int J Tuberc Lung Dis. 2000 Aug;4(8):771-5.PMID: 10949330 [PubMed - indexed for MEDLINE]

    8. Kasvosve I, Gangaidzo IT, Gomo ZA, Gordeuk VR. African iron overload.Acta Clin Belg. 2000 Mar-Apr;55(2):88-93. Review.PMID: 10881373 [PubMed - indexed for MEDLINE]

    7. Deharo E, Loyevsky M, John C, Balanza E, Ruiz G, Mu ñoz V, Gordeuk VR. Aminothiol multidentate chelators against Chagas disease.Exp Parasitol. 2000 Mar;94(3):198-200.PMID: 10831386 [PubMed - indexed for MEDLINE]

    6. Biemba G, Gordeuk VR, Thuma P, Weiss G. Markers of inflammation in children with severe malarial anaemia.Trop Med Int Health. 2000 Apr;5(4):256-62.PMID: 10810019 [PubMed - indexed for MEDLINE]

    5. Kasvosve I, Gomo ZA, Gangaidzo IT, Mvundura E, Saungweme T, Moyo VM, KhumaloH, Boelaert JR, Gordeuk VR, Delanghe JR. Reference range of serum haptoglobin is haptoglobin phenotype-dependent inblacks.Clin Chim Acta. 2000 Jun;296(1-2):163-70.PMID: 10807979 [PubMed - indexed for MEDLINE]

    4. Rana S, Houston P, Castro OL. Homocysteine levels and sickle cell anemia.J Pediatr Hematol Oncol. 2000 Mar-Apr;22(2):185; author reply 185-6. No abstract available.PMID: 10779039 [PubMed - indexed for MEDLINE]

    3. Hutagalung R, Wilairatana P, Looareesuwan S, Brittenham GM, Gordeuk VR. Influence of hemoglobin E trait on the antimalarial effect of artemisininderivatives.J Infect Dis. 2000 Apr;181(4):1513-6. Epub 2000 Apr 13.PMID: 10762587 [PubMed - indexed for MEDLINE]

    2. Biemba G, Dolmans D, Thuma PE, Weiss G, Gordeuk VR. Severe anaemia in Zambian children with Plasmodium falciparum malaria.Trop Med Int Health. 2000 Jan;5(1):9-16.PMID: 10672200 [PubMed - indexed for MEDLINE]

    1. Nekhai S, Shukla RR, Fernandez A, Kumar A, Lamb NJ. Cell cycle-dependent stimulation of the HIV-1 promoter by Tat-associated CAKactivator.Virology. 2000 Jan 20;266(2):246-56.PMID: 10639311 [PubMed - indexed for MEDLINE]

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